MELITTIN DERIVED PEPTIDE-DRUG CONJUGATE, M-DM1, INHIBITS TUMOR PROGRESSION AND INDUCES EFFECTOR CELL INFILTRATION IN MELANOMA BY TARGETING M2 TUMOR-ASSOCIATED MACROPHAGES

BackgroundMelanoma has the highest mortality 1976 corvette seat covers rate among all the types of skin cancer.In melanoma, M2-like tumor-associated macrophages (TAMs) are associated with the invasiveness of tumor cells and a poor prognosis.Hence, the depletion or reduction of M2-TAMs is a therapeutic strategy for the inhibition of tumor progressio

This research aims to provide a description, analysis, and interpretation of the values and integration of religious character education values of santri at Dayah Ummul Ayman Samalanga Bireuen Aceh.Based on the research questions, the method used is a qualitative approach with a case study design.The research locus was chosen at Dayah Ummul Ayman S

Microwave energy has been demonstrated to be able to assist mechanical rock breaking in geotechnical and mining engineering.The aim of this research is to study the influences of the interaction between microwave energy and rocks on the performance of disc cutters on a TBM (tunnel boring machine).By applying an open-type microwave-induced fracturin

BackgroundMany of the benefits of electronic health records (EHRs) have not been achieved at expected levels because of 1976 corvette seat covers a variety of unintended negative consequences such as documentation burden.Previous studies have characterized EHR use during and outside work hours, with many reporting that physicians spend considerable

Sung Bin Cho,1,* Yea-Jin Lee,2,* Sun Young Kang,3 Min Choi,3 Bora Kim,3 Jin-Chul Ahn2 1Yonsei Seran Dermatology and Laser Clinic, Seoul, Korea; 2Medical Laser Research Center, College of Medicine, Dankook University, Cheonan, Korea; 3R&D Center, Shenb Co., Ltd, Seoul, Korea*These authors contributed equally to this workCorrespondence: J